GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs2404602 | 1 | rs12594541 | chr15:76834368 | SCAPER | chr15:76640529-77197744:- | -0.2 | -4.41 | 1.35E-5 | Blood metabolite levels |
| BLCA | cis | rs9902453 | 1 | rs12600993 | chr17:28291222 | EFCAB5 | chr17:28256874-28435469:+ | 0.22 | 3.89 | 0.000117 | Coffee consumption (cups per day) |
| BLCA | cis | rs12608504 | 1 | rs12608504 | chr19:18389135 | KIAA1683 | chr19:18367906-18385319:- | -0.24 | -4.3 | 2.15E-5 | Waist-to-hip ratio adjusted for body mass index |
| BLCA | cis | rs12608504 | 1 | rs12610373 | chr19:18398284 | KIAA1683 | chr19:18367906-18385319:- | -0.24 | -4.38 | 1.56E-5 | Waist-to-hip ratio adjusted for body mass index |
| BLCA | cis | rs9677476 | 1 | rs12621280 | chr2:232132984 | ARMC9 | chr2:232063342-232238606:+ | 0.18 | 3.91 | 0.00011 | Food antigen IgG levels |
| BLCA | cis | rs10935120 | 1 | rs12637751 | chr3:134266124 | ANAPC13 | chr3:134196547-134204865:- | -0.5 | -7.97 | 1.89E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs12637751 | chr3:134266124 | CEP63 | chr3:134204575-134293852:+ | -0.24 | -4.09 | 5.33E-5 | Height |
| BLCA | cis | rs12638253 | 1 | rs12638253 | chr3:156626091 | LEKR1 | chr3:156544076-156763918:+ | -0.23 | -4.42 | 1.31E-5 | Multiple sclerosis (severity) |
| BLCA | cis | rs9815354 | 1 | rs12639255 | chr3:41861738 | ULK4 | chr3:41288091-42003660:- | 0.62 | 9.63 | 8.26E-20 | Diastolic blood pressure |
| BLCA | cis | rs7714584 | 1 | rs12652003 | chr5:150231945 | LOC134466 | chr5:150310000-150326146:- | 0.52 | 6.35 | 6.03E-10 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs12656538 | chr5:150251380 | LOC134466 | chr5:150310000-150326146:- | 0.54 | 6.52 | 2.24E-10 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs12656600 | chr5:150311872 | LOC134466 | chr5:150310000-150326146:- | 0.55 | 6.82 | 3.57E-11 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs12659118 | chr5:150324622 | LOC134466 | chr5:150310000-150326146:- | 0.55 | 6.63 | 1.18E-10 | Crohn's disease |
| BLCA | cis | rs1577917 | 1 | rs12661204 | chr6:86678586 | SNHG5 | chr6:86386726-86388451:- | -0.54 | -9.39 | 5.42E-19 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs12663651 | chr6:86701655 | SNHG5 | chr6:86386726-86388451:- | -0.49 | -8.73 | 7.95E-17 | Response to antipsychotic treatment |